Case Studies

Case Studies, Histopathology

Case of the Month: Hepatocutaneous Syndrome in a Cavalier King Charles Spaniel

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Clinical history Chucky was presented to the primary veterinary care practice with a 1 month history of hyperkeratosis, crusting and erythema of the skin of all four paws. A previous canine biochemical profile conducted at VPG revealed significantly elevated alkaline phosphatase (ALP), alanine transaminase (ALT), glutamate dehydrogenase (GLDH) and bile acids. A small liver was…
Case Studies, Histopathology

Case of the Month: “Yellow fungus disease” in a bearded dragon (Pogona vitticeps)

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A 1 year old bearded dragon developed chronic crusty lesions over the body, face and tail. Skin biopsies were taken and submitted to VPG Histology for examination. This revealed epidermal hyperplasia and prominent hyperkeratosis, areas of superficial epidermal necrosis and a mild inflammatory infiltrate within the epidermis and dermis. Faint outlines of structures suspected to…
Case Studies, Histopathology

Case of the Month: Feline Cowpox

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Leo, 1 year old male Domestic Shorthair cat   Clinical history Leo presented with swelling of the left forepaw characterised by the presence of multiple cutaneous lesions with scabs and poor skin integrity. Histology Three punch biopsies of haired skin were submitted for histopathological examination. These samples showed extensive epidermal ulceration, and severe epidermal and…
Case Studies, Histopathology

Case of the month: lymphangiomatosis marmoset

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Ben, a 2 year old Marmoset monkey. Clinical history Ben had a history of a fluid-filled swelling in the mammary area. Previously, fluid was sampled and was found to be of low cellularity. Lesions progressed with erythematous skin and secondary pyoderma over the entire ventrum and thickened, sore scrotal skin. Histology The biopsies submitted were…
Case Studies, Histopathology

Case of the Month: Scuticociliatosis in seahorses

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Multiple sudden deaths were reported in a population of captive seahorses (Hippocampus abdominalis). Histological examination revealed numerous ovoid to pear-shaped ciliated protozoal organisms measuring approximately 25×15 µm with a single nucleus. These were most numerous in subcutaneous fibrous connective tissue and muscle, but were also found within other tissues including the brain. The histological features…
Case Studies, Histopathology

Case of the Month: Feline Congenital Hepatic Fibrosis

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Bertie, a 7 year old male neutered Domestic Shorthair cat Clinical history Bertie presented with chronic vomiting, intermittently reduced appetite and weight loss. Liver enzymes were increased and the liver had an abnormal appearance on ultrasound. Histology Histologically, the normal hepatic tissue architecture was disturbed by moderate to marked expansion of portal tracts, which were…
Case Studies, Histopathology

Case of the Month: Aneurysmal Bone Cyst

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Priscilla, an 11 year old female neutered Labrador Retriever. Clinical history: Priscilla presented with a two-month history of left thoracic limb lameness and a palpable mass over the left scapula. CT scan showed an osteodestructive lesion, which was suspected to be a primary bone tumour. No metastasis was detected on staging. The entire left thoracic…
Case Studies, Histopathology

Case of the Month – Copper Hepatitis

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Name, signalment: Freya, 4 year old female spayed Labrador Retriever Clinical history: Freya had an abnormal looking liver observed during laparoscopic spay. Serum biochemistry revealed decreased urea. Multiple biopsies were obtained from the liver and submitted for histology. Histology: Depending on the biopsy evaluated, there was significant distortion of the lobular architecture of the liver….
Case Studies, Histopathology

Case of the Month: Trunk Predominant Pemphigus foliaceus

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Sukie, a 12 year old female intact cross breed dog Clinical history Sukie presented with multiple highly pruritic lesions on the dorsum between the thoracic and lumbar spine and some smaller lesions distributed across the back over the last 2 months. Some lesions resolved with antibiotic treatment, while others remained. She had a bout of…